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Natural Products & Medicinal Chemistry Research Group


Full List Publications

Selected Publications


  • G. Theodoridis, …, M. Halabalaki, E. Mikros and on behalf of the FoodOmicsGR_RI Consortium, FoodOmicsGR_RI: A Consortium for Comprehensive Molecular Characterisation of Food Products, Metabolites 2021, doi: 10.3390/metabo11020074
  • Aikaterina L. Stefi, Theodora Nikou, Dido Vassilacopoulou, Alexios-Leandros Skaltsounis, Maria Halabalaki, Nikolaos S. Christodoulakis, “Structure and organization of the secretion apparatus of the mastic tree (Pistacia lentiscus L.) and LC–HRMS analysis of leaf extracts”, Planta, 2021, doi: 10.1007/s00425-021-03588-2
  • Dimitris Michailidis, Apostolis Angelis, Panagiota Efstathia Nikolaou, Sofia Mitakou, Alexios-Leandros Skaltsounis, “Exploitation of Vitis vinifera, Foeniculum vulgare, Cannabis sativa and Punica granatum By-Product Seeds as Dermo-Cosmetic Agents”, Molecules, 2021, doi: 10.3390/molecules26030731
  • Maria Tsoumani, Anastasios Georgoulis, Panagiota-Efstathia Nikolaou, Ioannis V. Kostopoulos, Theano Dermintzoglou, Ioanna Papatheodorou, Anastasia Zoga, Panagiotis Efentakis, Maria Konstantinou, Evangelos Gikas, Nikolaos Kostomitsopoulos, Andreas Papapetropoulos, Antigone Lazou, Alexios-Leandros Skaltsounis, Derek J Hausenlov, Ourania Tsitsilonis, Ioulia Tseti, Fabio Di Lisa, Efstathios K Iliodromitis, Ioanna Andreadou, “Acute administration of the olive constituent, oleuropein, combined with ischemic postconditioning increases myocardial protection by modulating oxidative defense”, Free Radical Biology and Medicine, 2021, doi: 10.1016/j.freeradbiomed.2021.02.011
  • Katerina Gioti, Anastasia Papachristodoulou, Dimitra Benaki, Nektarios Aligiannis, Alexios-Leadros Skaltsounis, Emmanuel Mikros, Roxane Tenta, “Assessment of the Nutraceutical Effects of Oleuropein and the Cytotoxic Effects of Adriamycin, When Administered Alone and in Combination, in MG-63 Human Osteosarcoma Cells”, Nutrients, 2021, doi: 10.3390/nu13020354
  • Alexandros S. Zervas,Pavlos P. Lelovas, Antonios Galanos, Dimitrios Galanis, Maria Makropoulou, Stavros Beteinakis, Anastasia Patsaki, Christina Passali, Stavros K. Kourkoulis, Aggeliki Triantafyllou, Efstathios Chronopoulos, Allexios-Leandros Skaltsounis, Ismene Dontas, “The effect of table olive wastewater extract administration on the adult ovariectomised rat model of osteoporosis,” British Journal of Nutrition, 2021, doi: 10.1017/S0007114521000465
  • Atanas G. Atanasov, Sergey B. Zotchev, Verena M. Dirsch, the International Natural Product Sciences Taskforce & Claudiu T. Supuran, “Natural products in drug discovery: advances and opportunities”, Nature Reviews Drug Discovery , 2021, doi: 10.1038/s41573-020-00114- z
  • Konstantina Vougogiannopoulou, Angela Corona, Enzo Tramontano, Michael N. Alexis and Alexios-Leandros Skaltsounis, “Natural and Nature-Derived Products Targeting Human Coronaviruses”, Molecules, 2021, doi: 10.3390/molecules26020448


  • Georgia Sarikaki, Nikoleta Christoforidou, Nicolas Gaboriaud-Kolar,Amos B. Smith III, Ioannis K. Kostakis and Alexios-Leandros Skaltsounis, "Biomimetic Synthesis of Oleocanthal, Oleacein, and Their Analogues Starting from Oleuropein, A Major Compound of Olive Leaves", Journal Natural Products, 2020, doi: 10.1021/acs.jnatprod.0c00086
  • Aikaterina L. Stef, Dido Vassilacopoulou, Efthymia Routsi, Panagiotis Stathopoulos, Aikaterini Argyropoulou, Alexios‑Leandros Skaltsounis, Nikolaos S. Christodoulakis, “The Combined Environmental Stress on the Leaves of Olea europaea L. and the Relief Mechanism Through Biosynthesis of Certain Secondary Metabolites”, J. of Plant Growth Regulation, 2020, doi: 10.1007/s00344-020-10162-9
  • N. Kokras, A. Tsarbopoulos, A.-L. Skaltsounis and C. Dalla, “Behavioral and Neurochemical Effects of Extra Virgin Olive Oil Total Phenolic Content and Sideritis Extract in Female Mice”, Molecules ,2020, doi: 10.3390/molecules25215000
  • Evangelia Karkoula, Ioanna-Valentini Dagla, Eirini Baira, Nikolaos Kokras, Christina Dalla, Alexios-Leandros Skaltounis, Evagelos Gikas, Anthony Tsarbopoulos, “A novel UHPLC-HRMS-based metabolomics strategy enables the discovery of potential neuroactive metabolites in mice plasma, following i.p. administration of the main Crocus sativus L. bioactive component”, J. of Pharmaceutical and Biomedical Analysis 2020, doi: 10.1016/j.jpba.2019.112878
  • Stavros Beteinakis, Anastasia Papachristodoulou, Georgia Gogou, Sotirios Katsikis, Emmanuel Mikros, Maria Halabalaki, “NMR-Based Metabolic Profiling of Edible Olives-Determination of Quality Parameters”, Molecules, 2020, doi: 10.3390/molecules25153339